Big Picture

Trialbee: Innovating the fast-changing Clinical Trials landscape

The pressure to do trials quickly and efficiently has increased exponentially in the last year. It could be said that the increase has been proportional to the social recognition of the value that trials bring to health and well-being, to the expectations of patients to convert frequently fatal diseases into chronic ones, and to the desire of companies to maximize exploitation of drugs before patents expire.

A company in the US & Sweden is taking significant steps towards innovating the clinical trial front. It has introduced a platform for patient matching and enrollment. Trialbee brings a complete portal of tech-enabled services for Clinical Trial platforms, helping to boost the CT process in terms of speed and efficiency.

Trialbee remains a vibrant example of innovating Clinical Trial processes by working on the barriers and pushing technology to its boundaries where it continues to facilitate mankind.

In recent years, despite the slow pace of the main regulatory agencies (the Food and Drug Administration, in the US, and the European Medicines Agency, in Europe) to incorporate technological advances into clinical trials, there have been interesting changes such as the reduction of printed paper in data collection and the evolution towards electronic trials, including the electronic storage of clinical trial files, which It represents a great logistical saving, reduces space and improves access without reducing security.

Trialbee shows that progress has also been made towards electronic signatures, even though, to this day, there is still no compatible and universally accepted solution that pharmaceutical laboratories and hospital researchers can adopt at the same time.

For their part, communication and information technologies (ICT) have evolved so rapidly and have so much potential applied to clinical research that, currently, there is a debate on how ICT can be promoted to shorten and lower the cost of the development of therapeutic molecules and medical devices.

The capture of clinical trial data in real-time improves transparency (as it does to register and publish all clinical trials) and, at the same time, allows the decentralization of the trials; that is, it allows to carry out studies away from the hospital expanding the territory recruitment, increasing patient comfort and improving adherence to treatment.

It allows to integrate data from clinical trials with data from the real world – not only health but also socioeconomic, etc. – and build a system of a set of big data that, once integrated and analyzed, make it possible to make strategic decisions at the right time, whether it is the decision to continue developing a molecule or a decision with population (epidemiological) value.

Social networks facilitate the participation of patients in the drug development process and are one of the tools to always keep the patient in the center of focus.

In addition to the contributions of ICT, there have also been other scientific developments applied to medicine that have enriched the debate on improving the efficiency of clinical developments. Three good examples are precision medicine, adaptive designs, and collaborative initiatives:

  • Precision medicine allows each patient to be assigned the most appropriate treatment at the most appropriate dose and enables faster clinical trials with fewer patients.
  • Adaptive designs, which allow multiple hypotheses to be tested in a single study and make design modifications during the course of the study, based on the data, while allowing patients to change from an arm of the trial with an ineffective treatment to an arm where the treatment works.

With all these changes in the design of clinical trials (adaptive protocols), in the mechanisms for collecting data (real-time), in their integration and analysis (big data) and in the ways of financing the trials (public-private partnerships), we are living in a time of many transformations in the world of clinical research.

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Anna Papadopoulos
Anna Papadopoulos is a senior money, wealth, and asset management reporter at CEOWORLD magazine, covering consumer issues, investing and financial communities + author of the CEOWORLD magazine newsletter, writing about money with an enthusiasm unknown to mankind. You can follow CEOWORLD magazine on Twitter, Facebook, Instagram, or connect on LinkedIn for musings on money, wealth, asset management, millionaires, and billionaires. Email her at